Evidence-Based Medicine Working Group. User's guide to the medical literature: II. How to use an article about therapy or prevention. B. What were the results and will they help me caring for my patients. JAMA 1994;271(1):59-63. Disponível em: URL: http://www.cche.net/text/usersguides/therapy.asp

NNT: definition, calculation, example, converting.
Disponível em: URL: http://www.cebm.net/nnts.asp

Cenário 1 - JAMA

Ezekowitz MD, et al. for the Veterans Affrairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Investigatiors. Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrilation. New Eng J Med 1992 Nov 12;327(20):1406-1412.

Cenário 2 - Trombose venosa profunda

Hull RD, Raskob GE, Rosenbloom D, Panju AA, Brill-Edwards P, Ginsberg JS, Hirsh J, Martin GJ, Green D. Heparin for 5 days as compared with 10 days in the initial treatment of proximal venous thrombosis. N Engl J Med 1990 May 3;322(18):1260-1264.

Cenário 3 - Reanimação cardiorrespiratória

Hallstrom A, Cobb L, Johnson E, Copass M. Cardiopulmonary resuscitation by chest compression alone or with mouth-to-mouth ventilation. N Engl J Med 2000;342(21):1546-53.

1) Identificar e resumir os dados para calcular o efeito do tratamento;

2) Calcular o risco de evento no grupo experimental e no grupo controle; risco relativo, odds ratio, redução de risco relativo, redução de risco absoluto, número necessário a tratar, e os respectivos intervalos de confiança de 95%;

3) Interpretar os resultados de um estudo sobre tratamento.

Evidence-Based Medicine Working Group. User's guide to the medical literature: II. How to use an article about therapy or prevention. A. Are the results os the study valid? JAMA 1993; 270(21):2598-2601. Disponível em: URL: http://www.cche.net/principles/content_all.asp

Greenhalgh T. How to read a paper: papers that report drug trials. BMJ 1997 Aug 23;315:480-483. Disponível em: URL: http://www.bmj.com/collections/read.shtml

Haynes RB, Mulrow CD, Huth EJ, Altman DG, Gardner MJ. More Informative Abstracts Revisited. Ann Intern Med 1990;113:69-76. Disponível em: URL: http://www.acponline.org/journals/resource/90aim.htm

Sackett DL. Readers' guides for therapy: was the assignment of patients to treatments randomized? [Editorial]. ACP Journal Club. 1991 May-June;114:A-12.

Sackett DL, Haynes RB. Summarising the effects of therapy: a new table and some more terms [Editorial]. ACP Journal Club. 1997 Jul-Aug;127:A-15. Evidence-Based Medicine. 1997 Jul-Aug;2:103.

http://www.healthcare.ubc.ca/calc/clinsig.html
Clinical calculator. Welcome to the UBC clinical significance calculator

http://www.evidencias.com/cc_glossary_traducao_412.PDF
Glossário de termos de metodologia

http://www.cebm.net/levels_of_evidence.asp
Levels of evidence and grades of recommendation, Centre for Evidence-Based Medicine, Oxford, UK.